儿童克罗恩病早期筛查和诊断研究进展

doi:10.12372/jcp.2023.22e0604

摘要/Abstract

摘要：

克罗恩病（CD）是一种慢性非特异性胃肠道炎症性疾病。儿童CD起病隐匿，临床表现缺乏特异性，早期诊断困难，导致并发症、手术率和致残率增加。早期筛查和诊断、及时干预可改善患儿的治疗效果和预后，提高患儿生存质量。文章就儿童CD的早期筛查和诊断进展进行综述。

关键词: 克罗恩病, 血清标志物, 肠道微生物, 代谢组学, 儿童

Abstract:

Crohn's disease (CD) is a chronic nonspecific gastrointestinal inflammatory disease. The onset of CD in children is insidious, the clinical manifestations are lack of specificity, and early diagnosis is difficult, which leads to the increased complications, surgical rates and disability rates. Early screening and diagnosis, timely intervention can improve the therapeutic effect and prognosis of children, and improve the life quality of children. This article reviews the progress of early screening and diagnosis of CD in children.

Key words: Crohn's disease, serum marker, intestinal microorganisms, metabonomics, child

汪陈慧, 杨辉. 儿童克罗恩病早期筛查和诊断研究进展[J]. 临床儿科杂志, 2023, 41(9): 708-714.

Reviewer: WANG Chenhui, Reviser: YANG Hui. Research progress on early screening and diagnosis of Crohn's disease in children[J]. Journal of Clinical Pediatrics, 2023, 41(9): 708-714.

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