Journal of Clinical Pediatrics ›› 2026, Vol. 44 ›› Issue (3): 270-276.doi: 10.12372/jcp.2026.25e1575
• Literature Review • Previous Articles
GAN Xinyan1, LI Xiang1, QIU Qianyi2, CHEN Fang1(
)
Received:2025-12-15
Accepted:2026-01-22
Published:2026-03-15
Online:2026-03-06
CLC Number:
GAN Xinyan, LI Xiang, QIU Qianyi, CHEN Fang. Progress in prevention and management strategies of postoperative nausea and vomiting in pediatric day surgery[J].Journal of Clinical Pediatrics, 2026, 44(3): 270-276.
| [1] |
Kovac AL. Postoperative nausea and vomiting in pediatric patients[J]. Paediatr Drugs, 2021, 23(1): 11-37.
doi: 10.1007/s40272-020-00424-0 pmid: 33108649 |
| [2] |
Gan TJ, Belani KG, Bergese S, et al. Fourth consensus guidelines for the management of postoperative nausea and vomiting[J]. Anesth Analg, 2020, 131(2): 411-448.
doi: 10.1213/ANE.0000000000004833 pmid: 32467512 |
| [3] | 马洪升, 程南生, 朱涛, 等. 华西医院日间手术快速康复(ERAS)规范[J]. 中国胸心血管外科临床杂志, 2016, 23(2): 104-106. |
| Ma HS, Cheng NS, Zhu T, et al. Standard of enhanced recovery after surgery for day surgery in West China Hospital[J]. Zhongguo Xiongxinxueguan Waike Linchuang Zazhi, 2016, 23(2): 104-106. | |
| [4] |
Kim MS, Lee JR, Choi EM, et al. Association of 5-HT3B receptor gene polymorphisms with the efficacy of ondansetron for postoperative nausea and vomiting[J]. Yonsei Med J, 2015, 56(5): 1415-1420.
doi: 10.3349/ymj.2015.56.5.1415 |
| [5] |
Sayed JA, F Riad MA, M Ali MO. Comparison of dexamethasone or intravenous fluids or combination of both on postoperative nausea, vomiting and pain in pediatric strabismus surgery[J]. J Clin Anesth, 2016, 34: 136-142.
doi: 10.1016/j.jclinane.2016.03.049 pmid: 27687360 |
| [6] |
Messerer B, Stijic M, Sandner-Kiesling A, et al. Is PONV still a problem in pediatric surgery: a prospective study of what children tell us[J]. Front Pediatr, 2023, 11: 1241304.
doi: 10.3389/fped.2023.1241304 |
| [7] |
Sümer I, Uysal H, Yeşiltaş S, et al. The effect of intraoperative body temperature on postoperative nausea and vomiting in pediatric patients[J]. J Perianesth Nurs, 2021, 36(6): 706-710.
doi: 10.1016/j.jopan.2021.04.012 pmid: 34362639 |
| [8] |
Ashok V, Bala I, Bharti N, et al. Effects of intraoperative liberal fluid therapy on postoperative nausea and vomiting in children-A randomized controlled trial[J]. Paediatr Anaesth, 2017, 27(8): 810-815.
doi: 10.1111/pan.13179 pmid: 28585750 |
| [9] |
Mou Y, Zhao W, Pan W, et al. A comparison of ondansetron in preventing postoperative nausea and vomiting for patients with or without preoperative anxiety with painless egg retrieval: a prospective, randomized, controlled trial[J]. Gland Surg, 2024, 13(8): 1522-1534.
doi: 10.21037/gs-24-175 pmid: 39282027 |
| [10] |
Pomicino L, Maccacari E, Buchini S. Levels of anxiety in parents in the 24 hr before and after their child's surgery: a descriptive study[J]. J Clin Nurs, 2018, 27(1-2): 278-287.
doi: 10.1111/jocn.13895 pmid: 28544343 |
| [11] |
Eberhart LH, Morin AM, Guber D, et al. Applicability of risk scores for postoperative nausea and vomiting in adults to paediatric patients[J]. Br J Anaesth, 2004, 93(3): 386-392.
doi: 10.1093/bja/aeh221 |
| [12] |
Hou M, Wu L, Wei Z, et al. Elevated serum pepsinogen level predicts postoperative nausea and vomiting and pain in females with obesity following laparoscopic sleeve gastrectomy[J]. Int J Obes (Lond), 2025, 49(4): 665-672.
doi: 10.1038/s41366-024-01688-z |
| [13] |
Fan D, Yin Q, Li D, et al. Development and validation of a machine learning-based predictive model for postoperative nausea and vomiting in patients undergoing day-case laparoscopic cholecystectomy: a single-centre retrospective study[J]. BMJ Open, 2025, 15(10): e093884.
doi: 10.1136/bmjopen-2024-093884 |
| [14] |
Huddart R, Altman RB, Klein TE. PharmGKB summary: Ondansetron and tropisetron pathways, pharmacokinetics and pharmacodynamics[J]. Pharmacogenet Genomics, 2019, 29(4): 91-97.
doi: 10.1097/FPC.0000000000000369 |
| [15] | Chen H, Sun L, Zheng J, et al. Palonosetron versus tropisetron with dexamethasone for prevention of postoperative nausea and vomiting in pediatric adeno-tonsillectomy: a single center, randomized controlled trial[J]. Front Med (Lausanne), 2025, 12: 1549619. |
| [16] |
Singh PM, Borle A, Gouda D, et al. Efficacy of palonosetron in postoperative nausea and vomiting (PONV)-a meta-analysis[J]. J Clin Anesth, 2016, 34: 459-482.
doi: 10.1016/j.jclinane.2016.05.018 pmid: 27687434 |
| [17] | Steward DL, Grisel J, Meinzen-Derr J. Steroids for improving recovery following tonsillectomy in children[J]. Cochrane Database Syst Rev, 2011, 2011(8): CD003997. |
| [18] | Murakami C, Kakuta N, Satomi S, et al. Neurokinin-1 receptor antagonists for postoperative nausea and vomiting: a systematic review and meta-analysis[J]. Braz J Anesthesiol, 2020, 70(5): 508-519. |
| [19] |
Sun J, Cao X, Lu T, et al. Penehyclidine mitigates postoperative nausea and vomiting and intraoperative oculocardiac reflex in patients undergoing strabismus surgery: a prospective, randomized, double-blind comparison[J]. BMC Anesthesiol, 2021, 21(1): 49.
doi: 10.1186/s12871-021-01266-0 pmid: 33581727 |
| [20] |
Chiang FW, Chang JL, Hsu SC, et al. Dexmedetomidine use in pediatric strabismus surgery: A systematic review and meta-analysis[J]. PLoS One, 2020, 15(10): e0240553.
doi: 10.1371/journal.pone.0240553 |
| [21] | 范小丽, 贺伟忠, 苏凡. 眼科日间手术患儿术前2h口服清饮对术后恶心呕吐的影响[J]. 护理学杂志, 2017, 32(2): 38-40. |
| Fan XL, He WZ, Su F. Impact of oral intake of clear liquids two hours before ophthalmic day surgery on postoperative nausea and vomiting in children[J]. Hulixue Zazhi, 2017, 32(2): 38-40. | |
| [22] | 金芝芝, 王闰平, 王雅静, 等. 虚拟现实技术在儿童医疗辅导中的应用进展[J]. 中国护理管理, 2024, 24(12): 1863-1867. |
| Jin ZZ, Wang RP, Wang YP, et al. Application progress on virtual reality in child life[J]. Zhongguo Huli Guanli, 2024, 24(12): 1863-1867. | |
| [23] |
Xiao H, Ying H, Wang Y, et al. Application of the information-motivation-behavioral skill model in the perioperative period of pediatric day-case surgery[J]. J Surg Res, 2025, 313: 112-119.
doi: 10.1016/j.jss.2025.06.012 pmid: 40669369 |
| [24] |
Nathan N. Propofol: a superior strategy for PONV[J]. Anesth Analg, 2024, 139(1): 25.
doi: 10.1213/ANE.0000000000007065 pmid: 38885395 |
| [25] |
Frelich M, Sklienka P, Romanová T, et al. The effect of BIS-guided anaesthesia on the incidence of postoperative nausea and vomiting in children: a prospective randomized double-blind study[J]. BMC Anesthesiol, 2024, 24(1): 228.
doi: 10.1186/s12871-024-02610-w pmid: 38982400 |
| [26] |
Puri S, Bandyopadhyay A, Ashok V. Supplemental intraoperative crystalloids for pediatric postoperative nausea and vomiting-A systematic review and meta-analysis[J]. Paediatr Anaesth, 2023, 33(1): 38-45.
doi: 10.1111/pan.v33.1 |
| [27] |
Benhamou D. Postoperative nausea and vomiting: is the big little problem becoming a smaller little problem?[J]. Br J Anaesth, 2023, 131(1): 22-25.
doi: 10.1016/j.bja.2023.04.004 pmid: 37179157 |
| [28] |
Mieszczański P, Jurczak M, Cylke R, et al. Evidence-based perioperative prevention of postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic bariatric surgery: a scoping review[J]. J Clin Med, 2025, 14(19): 6901.
doi: 10.3390/jcm14196901 |
| [29] |
Yang XY, Xiao J, Chen YH, et al. Dexamethasone alone vs in combination with transcutaneous electrical acupoint stimulation or tropisetron for prevention of postoperative nausea and vomiting in gynaecological patients undergoing laparoscopic surgery[J]. Br J Anaesth, 2015, 115(6): 883-889.
doi: 10.1093/bja/aev352 pmid: 26507494 |
| [30] | Griffin K L, Svetanoff W J, Diefenbach K, et al. Implementation of an ERAS protocol for pediatric metabolic and bariatric surgery: a single institutional perspective and lessons learned[J]. J Pediatr Surg, 2024, 6: 100131. |
| [31] |
Moser JJ, Walker AM, Spencer AO. Point-of-care paediatric gastric sonography: can antral cut-off values be used to diagnose an empty stomach?[J]. Br J Anaesth, 2017, 119(5): 943-947.
doi: 10.1093/bja/aex249 pmid: 29028915 |
| [32] |
Chatterjee S, Arora RC, Crisafi C, et al. State of the art: proceedings of the American association for thoracic surgery enhanced recovery after cardiac surgery summit[J]. JTCVS Open, 2023, 14: 205-213.
doi: 10.1016/j.xjon.2023.04.004 pmid: 37425466 |
| [33] | Kim S, Song Y. Effects of early oral hydration on postextubation thirst, nausea, and vomiting in cardiac surgery patients: a randomized controlled trial[J]. J Perianesth Nurs, 2025, S1089-9472(25)00168-6. |
| [34] |
Kang MR, Seo HJ, Lee JS, et al. The effects of early oral intake in the postanesthesia care unit on nausea and vomiting: a meta-analysis of randomized controlled trials[J]. J Perianesth Nurs, 2025, 40(5): 1366-1374.
doi: 10.1016/j.jopan.2025.01.001 |
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