呼出气一氧化氮在儿童呼吸系统过敏性疾病诊断和治疗中的应用

doi:10.12372/jcp.2022.23e0182

Abstract

WU Jinhong. Application of exhaled nitric oxide in the diagnosis and treatment of respiratory allergic diseases in children[J].Journal of Clinical Pediatrics, 2023, 41(5): 328-332.

Figures/Tables 2

References 43

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年龄	<切点（低值）	临界值	≥切点（高值）
>12岁	<25	25~50	>50
≤12岁	<20	20~35	>35
临床意义	非嗜酸粒细胞性气道炎症	结合临床	嗜酸粒细胞性气道炎症

FeNO	哮喘			慢性咳嗽治疗指导	变应性鼻炎诊断
FeNO	诊断	治疗指导	新发预测	慢性咳嗽治疗指导	变应性鼻炎诊断
<20~25 ppb	非过敏性哮喘或诊断有误	初始治疗提示糖皮质激素治疗效果不佳，哮喘治疗过程中提示近期控制良好	未来发生过敏性哮喘的可能性小	糖皮质激素治疗无效	非变应性鼻炎或诊断有误
临界值	结合临床
>35~50 ppb	过敏性哮喘	初始治疗提示糖皮质激素治疗有效，哮喘治疗过程中提示控制不佳，存在哮喘急性发作风险	未来发生过敏性哮喘的可能性大	糖皮质激素治疗有效	变应性鼻炎

Application of exhaled nitric oxide in the diagnosis and treatment of respiratory allergic diseases in children

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