Journal of Clinical Pediatrics ›› 2023, Vol. 41 ›› Issue (5): 345-352.doi: 10.12372/jcp.2023.22e1353
• Respiratory Disease • Previous Articles Next Articles
YANG Shuhui, LIU Yulin(
), YANG Fan, LUO Zhengxiu, LIU Enmei
Received:2022-10-10
Published:2023-05-15
Online:2023-05-10
Contact:
LIU Yulin
E-mail:liuyulin817@163.com
YANG Shuhui, LIU Yulin, YANG Fan, LUO Zhengxiu, LIU Enmei. Effect of respiratory rehabilitation on children with bronchial asthma: a prospective randomized controlled study[J].Journal of Clinical Pediatrics, 2023, 41(5): 345-352.
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| 项 目 | 试验组(n=31) | 对照组(n=26) | 统计量 | P |
|---|---|---|---|---|
| 年龄(x±s)/岁 | 9.2±2.0 | 9.5±2.6 | t=0.49 | 0.628 |
| 男性[n(%)] | 21(67.7) | 17(65.4) | χ2=0.04 | 0.851 |
| 病程[M(P25~P75)]/年 | 4.0(2.8~6.0) | 4.0(1.9~5.0) | Z=0.43 | 0.668 |
| 身高(x±s)/cm | 137.6±12.0 | 138.9±15.2 | t=0.38 | 0.706 |
| 体重(x±s)/kg | 33.7±10.7 | 33.1±10.6 | t=0.23 | 0.816 |
| 体质指数[M(P25~P75)]/kg·m-2 | 17.2(14.6~20.7) | 16.4(14.2~18.8) | Z=1.28 | 0.200 |
| 主要照护者年龄[M(P25~P75)]/岁 | 37.0(35.0~39.3) | 38.5(34.8~44.0) | Z=0.24 | 0.810 |
| 主要照护者受教育程度[n(%)] | Z=0.82 | 0.410 | ||
| 高中/中专及以下 | 7(22.6) | 11(42.3) | ||
| 大学/大专 | 24(77.4) | 12(46.2) | ||
| 研究生 | 0(0) | 3(11.5) | ||
| 哮喘对家庭经济影响[n(%)] | Z=1.46 | 0.144 | ||
| 没有影响 | 14(45.2) | 4(15.4) | ||
| 轻度影响 | 11(35.5) | 19(73.1) | ||
| 中度影响 | 6(19.4) | 2(7.7) | ||
| 重度影响 | 0(0) | 1(3.8) | ||
| 吸入药物[n(%)] | χ2=7.06 | 0.115 | ||
| 丙酸氟替卡松气雾剂50μg | 3(9.7) | 0(0) | ||
| 丙酸氟替卡松气雾剂125μg | 2(6.5) | 4(15.4) | ||
| 沙美特罗替卡松气雾剂125μg | 13(41.9) | 5(19.2) | ||
| 沙美特罗替卡松粉吸入剂100μg | 10(32.3) | 12(46.2) | ||
| 布地奈德福莫特罗吸入粉雾剂80μg | 3(9.7) | 5(19.2) | ||
| 吸入药物频率[n(%)] | χ2=0.57 | 0.452 | ||
| 1次/d | 15(48.4) | 10(38.5) | ||
| 2次/d | 16(51.6) | 16(61.5) |
"
| 组 别 | 例数 | 6MWD/m | t值 | P | HR/次 | t值 | P | ||
|---|---|---|---|---|---|---|---|---|---|
| 干预前 | 干预后 | 干预前 | 干预后 | ||||||
| 试验组 | 31 | 574.0±79.6 | 610.2±68.0 | 4.62 | <0.001 | 117.3±20.0 | 109.0±16.0 | 2.45 | 0.021 |
| 对照组 | 26 | 587.7±71.5 | 574.7±58.6 | 1.33 | 0.195 | 115.6±17.8 | 117.2±13.3 | 0.70 | 0.492 |
| t值 | 0.68 | 2.09 | 0.35 | 2.09 | |||||
| P | 0.499 | 0.041 | 0.731 | 0.042 | |||||
| 组 别 | 例数 | SBP/mmHg | t值 | P | DBP/mmHg | t值 | P | ||
| 干预前 | 干预后 | 干预前 | 干预后 | ||||||
| 试验组 | 31 | 124.5±15.4 | 119.9±13.0 | 2.19 | 0.036 | 67.6±8.0 | 66.2±6.4 | 1.05 | 0.304 |
| 对照组 | 26 | 127.0±15.7 | 123.2±13.6 | 1.53 | 0.139 | 67.1±8.1 | 67.4±8.6 | 0.17 | 0.870 |
| t值 | 0.59 | 0.93 | 0.25 | 0.56 | |||||
| P | 0.557 | 0.355 | 0.803 | 0.576 | |||||
"
| 组 别 | 例数 | FVC/% | t值 | P | FEV1/% | t值 | P | ||
|---|---|---|---|---|---|---|---|---|---|
| 干预前 | 干预后 | 干预前 | 干预后 | ||||||
| 试验组 | 31 | 91.2±14.4 | 95.0±10.6 | 2.38 | 0.024 | 83.7±16.4 | 88.5±12.7 | 2.87 | 0.008 |
| 对照组 | 26 | 92.5±13.1 | 95.8±9.1 | 1.80 | 0.084 | 84.3±14.3 | 89.9±10.1 | 2.42 | 0.023 |
| t值 | 0.36 | 0.28 | 0.15 | 0.48 | |||||
| P | 0.724 | 0.777 | 0.880 | 0.623 | |||||
| 组 别 | 例数 | FEV1/FVC/% | t值 | P | PEF/% | t值 | P | ||
| 干预前 | 干预后 | 干预前 | 干预后 | ||||||
| 试验组 | 31 | 91.0±9.8 | 92.6±8.9 | 1.32 | 0.196 | 85.0±17.9 | 92.6±8.9 | 3.71 | 0.001 |
| 对照组 | 26 | 90.9±7.8 | 94.1±7.2 | 2.32 | 0.029 | 86.0±14.1 | 89.0±12.1 | 1.60 | 0.121 |
| t值 | 0.04 | 0.67 | 0.22 | 1.01 | |||||
| P | 0.968 | 0.504 | 0.829 | 0.317 | |||||
| 组 别 | 例数 | MEF75/% | t值 | P | MEF50/% | t值 | P | ||
| 干预前 | 干预后 | 干预前 | 干预后 | ||||||
| 试验组 | 31 | 73.9±20.0 | 81.3±20.2 | 2.71 | 0.011 | 57.3±17.6 | 64.0±17.5 | 2.36 | 0.025 |
| 对照组 | 26 | 73.2±17.2 | 81.8±14.8 | 3.06 | 0.005 | 57.0±16.7 | 64.8±14.2 | 2.60 | 0.015 |
| t值 | 0.13 | 0.12 | 0.06 | 0.18 | |||||
| P | 0.895 | 0.902 | 0.950 | 0.860 | |||||
| 组 别 | 例数 | MEF25/% | t值 | P | MMEF75/25/% | t值 | P | ||
| 干预前 | 干预后 | 干预前 | 干预后 | ||||||
| 试验组 | 31 | 46.0±15.8 | 51.5±16.0 | 1.99 | 0.055 | 54.9±17.1 | 61.2±17.0 | 2.24 | 0.032 |
| 对照组 | 26 | 46.3±13.6 | 54.6±17.0 | 2.79 | 0.010 | 55.1±15.9 | 63.7±15.6 | 2.99 | 0.006 |
| t值 | 0.07 | 0.72 | 0.03 | 0.58 | |||||
| P | 0.944 | 0.477 | 0.973 | 0.566 | |||||
"
| 组 别 | 例数 | 哮喘模块(家长版)/分 | Z值 | P | 哮喘模块(患儿版)/分 | Z值 | P | ||
|---|---|---|---|---|---|---|---|---|---|
| 干预前 | 干预后 | 干预前 | 干预后 | ||||||
| 试验组 | 31 | 15.0(7.8~28.3) | 7.0(5.0~10.3) | 3.72 | <0.001 | 17.5(13.0~25.8) | 10.0(7.5~12.0) | 4.17 | <0.001 |
| 对照组 | 26 | 18.5(6.8~28.3) | 13.5(4.8~23.3) | 0.98 | 0.327 | 15.0(9.5~19.0) | 13.5(6.8~18.3) | 0.18 | 0.854 |
| Z值 | 0.22 | 2.22 | 1.46 | 2.02 | |||||
| P | 0.829 | 0.026 | 0.144 | 0.044 | |||||
| 组 别 | 例数 | 普适模块(家长版)/分 | Z值 | P | 普适模块(患儿版)/分 | Z值 | P | ||
| 干预前 | 干预后 | 干预前 | 干预后 | ||||||
| 试验组 | 31 | 19.5(7.8~22.8) | 10.0(2.0~12.3) | 3.32 | 0.001 | 19.0(9.5~21.3) | 8.5(6.8~13.3) | 3.79 | <0.001 |
| 对照组 | 26 | 15.0(10.8~26.3) | 12.5(6.0~24.3) | 0.75 | 0.452 | 14.0(9.0~21.5) | 12(7.0~17.3) | 1.26 | 0.209 |
| Z值 | 0.09 | 2.35 | 0.70 | 2.16 | |||||
| P | 0.930 | 0.019 | 0.485 | 0.031 | |||||
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